<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.1 plus MathML 2.0 plus SVG 1.1//EN" "http://www.w3.org/2002/04/xhtml-math-svg/xhtml-math-svg.dtd">
<html xmlns="http://www.w3.org/1999/xhtml">
  <head>
    <meta http-equiv="Content-Type" content="application/xhtml+xml; charset=utf-8"/>
    <title>Project-Team:DEFI</title>
    <link rel="stylesheet" href="../static/css/raweb.css" type="text/css"/>
    <meta name="description" content="Research Program - Research Program"/>
    <meta name="dc.title" content="Research Program - Research Program"/>
    <meta name="dc.subject" content=""/>
    <meta name="dc.publisher" content="INRIA"/>
    <meta name="dc.date" content="(SCHEME=ISO8601) 2016-01"/>
    <meta name="dc.type" content="Report"/>
    <meta name="dc.language" content="(SCHEME=ISO639-1) en"/>
    <meta name="projet" content="DEFI"/>
    <script type="text/javascript" src="https://raweb.inria.fr/rapportsactivite/RA2016/static/MathJax/MathJax.js?config=TeX-MML-AM_CHTML">
      <!--MathJax-->
    </script>
  </head>
  <body>
    <div class="tdmdiv">
      <div class="logo">
        <a href="http://www.inria.fr">
          <img style="align:bottom; border:none" src="../static/img/icons/logo_INRIA-coul.jpg" alt="Inria"/>
        </a>
      </div>
      <div class="TdmEntry">
        <div class="tdmentete">
          <a href="uid0.html">Project-Team Defi</a>
        </div>
        <span>
          <a href="uid1.html">Members</a>
        </span>
      </div>
      <div class="TdmEntry">
        <a href="./uid3.html">Overall Objectives</a>
      </div>
      <div class="TdmEntry">Research Program<ul><li class="tdmActPage"><a href="uid13.html&#10;&#9;&#9;  ">Research Program</a></li></ul></div>
      <div class="TdmEntry">Application Domains<ul><li><a href="uid15.html&#10;&#9;&#9;  ">Radar and GPR applications</a></li><li><a href="uid16.html&#10;&#9;&#9;  ">Biomedical imaging</a></li><li><a href="uid17.html&#10;&#9;&#9;  ">Non destructive testing and parameter identification</a></li><li><a href="uid18.html&#10;&#9;&#9;  ">Diffusion MRI</a></li></ul></div>
      <div class="TdmEntry">
        <a href="./uid20.html">Highlights of the Year</a>
      </div>
      <div class="TdmEntry">New Software and Platforms<ul><li><a href="uid25.html&#10;&#9;&#9;  ">FVforBlochTorrey</a></li><li><a href="uid28.html&#10;&#9;&#9;  ">InvGIBC</a></li><li><a href="uid31.html&#10;&#9;&#9;  ">RODIN</a></li><li><a href="uid34.html&#10;&#9;&#9;  ">Samplings-3d</a></li><li><a href="uid37.html&#10;&#9;&#9;  ">samplings-2d</a></li><li><a href="uid40.html&#10;&#9;&#9;  ">SAXS-EM</a></li></ul></div>
      <div class="TdmEntry">New Results<ul><li><a href="uid44.html&#10;&#9;&#9;  ">Methods for inverse problems</a></li><li><a href="uid52.html&#10;&#9;&#9;  ">Shape and topology optimization</a></li><li><a href="uid57.html&#10;&#9;&#9;  ">Direct scattering problems</a></li><li><a href="uid60.html&#10;&#9;&#9;  ">Asymptotic Analysis</a></li><li><a href="uid66.html&#10;&#9;&#9;  ">Diffusion MRI</a></li></ul></div>
      <div class="TdmEntry">Bilateral Contracts and Grants with Industry<ul><li><a href="uid74.html&#10;&#9;&#9;  ">Bilateral Contracts with Industry</a></li><li><a href="uid78.html&#10;&#9;&#9;  ">Bilateral Grants with Industry</a></li></ul></div>
      <div class="TdmEntry">Partnerships and Cooperations<ul><li><a href="uid83.html&#10;&#9;&#9;  ">National Initiatives</a></li><li><a href="uid87.html&#10;&#9;&#9;  ">International Initiatives</a></li><li><a href="uid96.html&#10;&#9;&#9;  ">International Research Visitors</a></li></ul></div>
      <div class="TdmEntry">Dissemination<ul><li><a href="uid112.html&#10;&#9;&#9;  ">Promoting Scientific Activities</a></li><li><a href="uid153.html&#10;&#9;&#9;  ">Teaching - Supervision - Juries</a></li></ul></div>
      <div class="TdmEntry">
        <div>Bibliography</div>
      </div>
      <div class="TdmEntry">
        <ul>
          <li>
            <a id="tdmbibentyear" href="bibliography.html">Publications of the year</a>
          </li>
        </ul>
      </div>
    </div>
    <div id="main">
      <div class="mainentete">
        <div id="head_agauche">
          <small><a href="http://www.inria.fr">
	    
	    Inria
	  </a> | <a href="../index.html">
	    
	    Raweb 
	    2016</a> | <a href="http://www.inria.fr/en/teams/defi">Presentation of the Project-Team DEFI</a> | <a href="http://www.cmap.polytechnique.fr/~defi/">DEFI Web Site
	  </a></small>
        </div>
        <div id="head_adroite">
          <table class="qrcode">
            <tr>
              <td>
                <a href="defi.xml">
                  <img style="align:bottom; border:none" alt="XML" src="../static/img/icons/xml_motif.png"/>
                </a>
              </td>
              <td>
                <a href="defi.pdf">
                  <img style="align:bottom; border:none" alt="PDF" src="IMG/qrcode-defi-pdf.png"/>
                </a>
              </td>
              <td>
                <a href="../defi/defi.epub">
                  <img style="align:bottom; border:none" alt="e-pub" src="IMG/qrcode-defi-epub.png"/>
                </a>
              </td>
            </tr>
            <tr>
              <td/>
              <td>PDF
</td>
              <td>e-Pub
</td>
            </tr>
          </table>
        </div>
      </div>
      <!--FIN du corps du module-->
      <br/>
      <div class="bottomNavigation">
        <div class="tail_aucentre">
          <a href="./uid3.html" accesskey="P"><img style="align:bottom; border:none" alt="previous" src="../static/img/icons/previous_motif.jpg"/> Previous | </a>
          <a href="./uid0.html" accesskey="U"><img style="align:bottom; border:none" alt="up" src="../static/img/icons/up_motif.jpg"/>  Home</a>
          <a href="./uid15.html" accesskey="N"> | Next <img style="align:bottom; border:none" alt="next" src="../static/img/icons/next_motif.jpg"/></a>
        </div>
        <br/>
      </div>
      <div id="textepage">
        <!--DEBUT2 du corps du module-->
        <h2>Section: 
      Research Program</h2>
        <h3 class="titre3">Research Program</h3>
        <p>The research activity of our team is dedicated to the design,
analysis and implementation of efficient numerical methods
to solve inverse and shape/topological optimization problems
in connection with wave imaging, structural design, non-destructive testing and
medical imaging modalities. We are particularly interested in the development of fast methods that
are suited for real-time applications and/or large scale problems. These goals
require to work on both the physical and the mathematical models involved and
indeed a solid expertise in related numerical algorithms.</p>
        <p>This section intends to give a general overview of our research interests
and themes.
We choose to present them through the specific academic example of
inverse scattering problems (from inhomogeneities), which is representative of
foreseen developments on both inversion and (topological) optimization
methods. The
practical problem would be to identify an inclusion
from measurements of diffracted waves that result from the interaction of the
sought inclusion with some (incident) waves sent into the probed medium. Typical applications
include biomedical imaging where using micro-waves one would like to probe the
presence of pathological cells, or
imaging of urban infrastructures where using ground penetrating radars (GPR)
one is interested in finding the location of buried facilities such as
pipelines or waste deposits. This kind of
applications requires in particular fast and reliable algorithms.</p>
        <p>By “imaging” we shall refer to the inverse problem where the concern is only the location and
the shape of the inclusion, while “identification” may also indicate getting
informations on the inclusion physical parameters.</p>
        <p>Both problems (imaging and identification) are non linear and
ill-posed (lack of stability with respect to measurements errors if some
careful constrains are not added). Moreover, the unique determination of the
geometry or the coefficients is not guaranteed in general if sufficient
measurements are not available. As an example, in the case of
anisotropic inclusions, one can show that an appropriate set of data uniquely
determine the geometry but not the material properties.</p>
        <p>These theoretical considerations (uniqueness, stability) are not only important in
understanding the mathematical properties of the inverse problem, but also
guide the choice of appropriate numerical strategies (which information can be
stably reconstructed) and also the design of appropriate regularization
techniques. Moreover, uniqueness proofs are in general constructive proofs,
i.e. they implicitly contain a numerical algorithm to solve the inverse problem, hence
their importance for practical applications. The sampling methods introduced
below are one example of such algorithms.</p>
        <p>A large part of our research activity is dedicated to numerical methods applied to the first
type of inverse problems, where only the geometrical information is sought. In
its general setting the inverse
problem is very challenging and no method can provide a universal satisfactory
solution to it (regarding the balance cost-precision-stability). This is why in
the majority of the practically employed algorithms, some simplification of the underlying mathematical
model is used, according to the specific configuration of the imaging
experiment. The most popular ones are geometric optics (the Kirchhoff approximation) for high frequencies
and weak scattering (the Born
approximation) for small contrasts or small obstacles. They actually give full satisfaction for a wide range of
applications as attested by the large success of existing imaging devices (radar, sonar, ultrasound, X-ray
tomography, etc.), that rely on one of these
approximations.</p>
        <p>Generally speaking, the used simplifications result in a linearization of
the inverse problem and therefore are usually valid only if the latter is
weakly non-linear. The development of these simplified models
and the improvement of their efficiency is still a very active research
area. With that perspective we are particularly interested in deriving and
studying higher order asymptotic models associated with small geometrical
parameters such as: small obstacles, thin coatings, wires, periodic media,
<span class="math"><math xmlns="http://www.w3.org/1998/Math/MathML"><mo>...</mo></math></span>. Higher order models usually introduce some non linearity in
the inverse problem, but are in principle easier to handle from the numerical
point of view than in the case of the exact model.</p>
        <p>A larger part of our research activity is dedicated to algorithms that
avoid the use of such approximations and that are efficient where classical
approaches fail: i.e. roughly speaking when the non linearity of the inverse problem is
sufficiently strong. This type of configuration is motivated by
the applications mentioned below, and occurs as soon as the geometry of the
unknown media generates non negligible multiple scattering effects
(multiply-connected and closely spaces obstacles) or when the used frequency is
in the so-called resonant region (wave-length comparable to the size of the
sought medium).
It is therefore much more
difficult to deal with and requires new approaches. Our ideas
to tackle this problem will be motivated and inspired by recent
advances in shape and topological optimization methods and also the
introduction of novel classes of imaging algorithms, so-called
sampling methods.</p>
        <p>The sampling methods are fast imaging solvers adapted to multi-static data (multiple receiver-transmitter pairs)
at a fixed frequency. Even if they do not use any linearization
the forward model, they rely on computing the solutions to a set
of linear problems of small size, that can be performed in a completely
parallel procedure. Our team has already a solid expertise in these methods
applied to electromagnetic 3-D problems. The success of such
approaches was their ability to provide a relatively quick algorithm for solving 3-D
problems without any need for a priori knowledge on the physical parameters of
the targets. These algorithms solve only the imaging problem, in the sense
that only the geometrical information is provided.</p>
        <p>Despite the large efforts already spent in the development of this type of
methods, either from the algorithmic point of view or the theoretical one,
numerous questions are still open. These attractive new algorithms also suffer from the
lack of experimental validations, due to their relatively recent introduction. We also would like to invest on this side by
developing collaborations with engineering research groups that have
experimental facilities. From the practical point of view, the most potential limitation of sampling methods
would be the need of a large amount of data to achieve a reasonable accuracy. On the
other hand, optimization methods do not suffer from this constrain but they require good
initial guess to ensure convergence and reduce the number of iterations. Therefore it seems
natural to try to combine the two class of methods in order to calibrate the balance between
cost and precision.</p>
        <p>Among various shape optimization methods, the Level Set method seems to be particularly
suited for such a coupling. First, because it shares similar mechanism as sampling
methods: the geometry is captured as a level set of an “indicator function” computed on a
cartesian grid. Second, because the two methods do not require any a priori knowledge on
the topology of the sought geometry. Beyond the choice of a particular method, the main
question would be to define in which way the coupling can be achieved. Obvious strategies
consist in using one method to pre-process (initialization) or post-process (find the level
set) the other. But one can also think of more elaborate ones, where for instance a sampling
method can be used to optimize the choice of the incident wave at each iteration step.The
latter point is closely related to the design of so called “focusing incident waves” (which
are for instance the basis of applications of the time-reversal principle). In the frequency
regime, these incident waves can be constructed from the eigenvalue decomposition of the
data operator used by sampling methods. The theoretical and numerical investigations
of these aspects are still not completely understood for electromagnetic or elastodynamic
problems.</p>
        <p>Other topological optimization methods, like the homogenization method or the
topological gradient method, can also be used, each one provides particular advantages
in specific configurations. It is evident that the
development of these methods is very suited to inverse problems and provide
substantial advantage compared to classical shape optimization methods based on
boundary variation. Their applications to inverse
problems has not been fully investigated. The efficiency of these optimization
methods can also be increased for adequate asymptotic configurations. For instance small
amplitude homogenization method can be used as an efficient relaxation method
for the inverse problem in the presence of small contrasts. On the other hand, the topological gradient method has
shown to perform well in localizing small inclusions with only one iteration.</p>
        <p>A broader perspective would be the extension of the
above mentioned techniques to time-dependent cases. Taking into account data in
time domain is important for many practical applications, such as imaging in cluttered media,
the design of absorbing coatings or also crash worthiness in the case of
structural design.</p>
        <p>For the identification problem, one would like to also have information on the physical
properties of the targets. Of course optimization methods is a tool of choice
for these problems. However, in some applications only a qualitative information
is needed and obtaining it in a cheaper way can be performed using
asymptotic theories combined with sampling methods. We also refer here to the use of
so called transmission
eigenvalues as qualitative indicators for non destructive testing of
dielectrics.</p>
        <p>We are also interested in parameter identification problems arising in
diffusion-type problems. Our research here is mostly motivated by applications
to the imaging of biological tissues with the technique of Diffusion
Magnetic Resonance Imaging (DMRI). Roughly speaking DMRI gives a measure of the average distance travelled by water molecules in a
certain medium and can give useful information on cellular structure and structural change
when the medium is biological tissue.
In particular, we would like to infer from DMRI measurements
changes in the cellular volume fraction
occurring upon various physiological or pathological conditions
as well as the average cell size in the case of tumor imaging. The main
challenges here are 1) correctly model measured signals using diffusive-type
time-dependent PDEs 2) numerically handle the complexity of the tissues 3)
use the first two to identify physically relevant parameters from
measurements. For the last point we are particularly interested in
constructing reduced models of the multiple-compartment Bloch-Torrey partial differential
equation using homogenization methods.</p>
      </div>
      <!--FIN du corps du module-->
      <br/>
      <div class="bottomNavigation">
        <div class="tail_aucentre">
          <a href="./uid3.html" accesskey="P"><img style="align:bottom; border:none" alt="previous" src="../static/img/icons/previous_motif.jpg"/> Previous | </a>
          <a href="./uid0.html" accesskey="U"><img style="align:bottom; border:none" alt="up" src="../static/img/icons/up_motif.jpg"/>  Home</a>
          <a href="./uid15.html" accesskey="N"> | Next <img style="align:bottom; border:none" alt="next" src="../static/img/icons/next_motif.jpg"/></a>
        </div>
        <br/>
      </div>
    </div>
  </body>
</html>
