Section: Highlights of the Year

Highlights of the Year

The Gilles Kahn accessits prize was awarded to Camille Marchet for her PhD thesis: From reads to transcripts: de novo methods for the analysis of transcriptome second and third generation sequencing [8]. This thesis was prepared in the GenScale team under the supervision of P. Peterlongo.

The Gilles Kahn prize is awarded each year by the SIF, the French Society of Computer Science, for an excellent PhD thesis in the field of computer science.

The thesis of Camille dealt with the processing of transcriptome sequencing data. More precisely, the question was how to take advantage of the characteristics of the data produced by third generation sequencing technologies, as they produce large sequences covering the total length of RNA molecules. The core work of this thesis consisted in the methodological development and implementation of new algorithms allowing the clustering of third generation sequences by gene, then their correction and finally the detection of the different isoforms of each gene.