Section: New Results

Recruitment Optimization in Clinical Trials : a Multi-Objective Combinatorial Optimization Problem

Participants : J. Jacques, L. Jourdan, C. Dhaenens.

This work focuses on helping clinical trials investigators to screen more patients. First, we performed an analysis of clinical trial business and medical data available in French hospitals. We carried on several expert interviews. Then we developed a model to this problem as an association rules mining problem. After a statistical study of rule interestingness measures, we proposed an improvement of this model as a multi-objective combinatorial optimization problem.