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Section: Partnerships and Cooperations

International projects

Table 10.
Project name French bioinformatics contribution to ICGC
Coordinator G. Thomas
IBIS participants F. Rechenmann
Type International Cancer Genome Consortium (ICGC)
Web page http://www.icgc.org//

The goal of ICGC (International Cancer Genome Consortium) is to obtain a comprehensive description of genomic, transcriptomic and epigenomic changes in 50 different cancer types. In France, INCa (French National Cancer Institute) contributes to this project and focuses on two types of cancer. The main idea is to sequence the human genome of normal and tumoral cells of a large set of patients and to compare these genomic sequences to identify the mutations which may explain the development of the cancers. Bioinformatics is clearly involved in the management, the analysis and the visualization of the huge sets of data and results. Bioinformatics of the French contribution is carried out at Lyon, in the context of the Synergie Lyon Cancer Foundation. Until this year, François Rechenmann was part of the bioinformatics team and contributed to the organization of the data management and analysis workflow, under the leadership of prof. Gilles Thomas.