Section: Partnerships and Cooperations

Regional Initiatives

DIGITEO Project (DIM LSC) ALMA

Project title: Mathematical Analysis of Acute Myeloid Leukemia (AML) and its treatments

September 2014 - August 2017

Coordinator: Catherine Bonnet, Disco team, Saclay-IdF

Other partners: Inria Paris-Rocquencourt (Mamba team), France, L2S, France, UPMC (LJLL), St Antoine Hospital, Paris

Abstract: this project follows the regional projects ALMA (2010-2014) and ALMA2 (2011-2013). Starting from the work of J. L. Avila Alonso's PhD thesis in ALMA the aim of this project is to provide a refined coupled model of healthy and cancer cell dynamics in AML whose (stability) analysis will enable evaluation of polychemiotherapies delivered in the case of AML which have a high level of Flt-3 duplication (Flt-3-ITD).