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Section: New Software and Platforms

High Performance Diffusion MRI

Keywords: Health - Neuroimaging - Medical imaging

Functional Description

We have been closely involved in pushing the frontiers of the diffusion MRI (dMRI) in the recent years, especially in the mathematical modelling and processing of the dMRI signal and have developed state-of-the-art software implementations in the form of a C++ library that can be effectively used to infer the complex microstructure of the cerebral white matter. These algorithms and software fall into four categories: (i) local tissue modelling, which includes both popular 2nd order models and advanced higher than 2nd order models such as DTI, higher order Cartesian tensors (HOTs), ODF, FOD, EAP, maxima extraction, regularization and segmentation, (ii) generation of scalar indices (or biomarkers), which include DTI biomarkers, Diffusion Kurtosis Imaging (DKI) and invariants of 4th order tensors, (iii) global structure estimation, which includes deterministic and probabilistic tractography, and (iv) data visualisation for scalar indices, local models and global structures. This library has been transfered to the company Olea Medical where it is currently under test and validation, thanks to the contributions of Aurobrata Ghosh.