Section: New Results

Modeling the Apelin Receptor

The Apelin receptor (ApelinR) is a GPCR which is important in regulating cardiovascular homeostasis. As part of an on-going collaboration with the Centre for Interdisciplinary Research (CIRB) at Collège de France, we modeled the interaction between the Apelin peptide and ApelinR [13] . This study provides new mechanistic insights which could lead to the development of therapeutic agents for the treatment of heart failure.