Section: New Software and Platforms
Genome Wide Association Study using Data Mining strategy
Keywords: GWAS - Data mining
Functional Description: From two cohorts of genotyped individuals (case and control), the GWASDM software performs a Genome Wide Association Study based on data mining techniques and generates several patterns of SNPs that correlate with a given phenotype. The algorithm implemented in GWASDM directly uses relative risk measures such as risk ratio, odds ratio and absolute risk reduction combined with confidence intervals as anti-monotonic properties to efficiently prune the search space. The algorithm discovers a complete set of discriminating patterns with regard to given thresholds or applies heuristic strategies to extract the largest statistically significant discriminating patterns in a given dataset.