Section: New Software and Platforms

aevol

Artificial Evolution

Keywords: Bioinformatics - Genomics - Evolution

Functional Description: Aevol is a digital genetics model: populations of digital organisms are subjected to a process of selection and variation, which creates a Darwinian dynamics. By modifying the characteristics of selection (e.g. population size, type of environment, environmental variations) or variation (e.g. mutation rates, chromosomal rearrangement rates, types of rearrangements, horizontal transfer), one can study experimentally the impact of these parameters on the structure of the evolved organisms. In particular, since Aevol integrates a precise and realistic model of the genome, it allows for the study of structural variations of the genome (e.g. number of genes, synteny, proportion of coding sequences).

The simulation platform comes along with a set of tools for analysing phylogenies and measuring many characteristics of the organisms and populations along evolution.

An extension of the model (R-Aevol), integrates an explicit model of the regulation of gene expression, thus allowing for the study of the evolution of gene regulation networks.

Release Functional Description: Fix compilation error on Mac (tr1 included in std). The new mac compiler includes the tr1 directly in std which caused a compilation error. This issue was specific to aevol-4.4.1

• Participants: Antoine Frénoy, Bérénice Batut, Carole Knibbe, David Parsons, Dusan Misevic, Guillaume Beslon, Jonathan Rouzaud-Cornabas and Vincent Liard

• Partners: UCBL Lyon 1 - INSERM - Université Paris-Descartes - Insa de Lyon

• Contact: Guillaume Beslon

• URL: http://www.aevol.fr/