Section: Application Domains

Clinical applications

After several validation steps – based on clinical and experimental data – we have reached the point of having validated the heart model in a pre-clinical context where we have combined direct and inverse modeling in order to bring predictive answers on specific patient states. For example, we have demonstrated the predictive ability of our model to set up pacemaker devices for a specific patient in cardiac resynchronization therapies, see [11]. We have also used our parametric estimation procedure to provide a quantitative characterization of an infarct in a clinical experiment performed with pigs, see [3].