Section: New Software and Platforms

NOLB

NOn-Linear rigid Block NMA method

Keywords: Structural Biology - Bioinformatics - Elasticity - Proteins - Motion analysis

Functional Description: It's a new conceptually simple and computationally efficient method for non-linear normal mode analysis of macromolecules.

Release Functional Description: Version 1.2 from January 2019: Exclusion interaction list added. Version 1.3 from April 2019: Sequence and structural alignment fixed thanks to Guillaume Pages. More advanced iterative structural alignment added. Version 1.4 from June 2019: Firt version of domain identification added. Please use the "–nDomains" option Version 1.5 from July 2019: Rigid block format updated. JSON and Text output formats added. Version 1.6 from December 2019: Added initial Voronota support.

• Participants: Sergei Grudinin and Alexandre Hoffmann

• Contact: Sergei Grudinin

• Publications: NOLB: Nonlinear Rigid Block Normal Mode Analysis Method - RapidRMSD: Rapid determination of RMSDs corresponding to motions of flexible molecules

• URL: https://team.inria.fr/nano-d/software/nolb-normal-modes/