Section: Software and Platforms

SACHA

Participants : Marie Chupin [Correspondant] , Ludovic Fillon.

SACHA (“Segmentation Automatisée Compétitive de l’Hippocampe et de l’Amygdale”) is a software for the fully automatic segmentation of the hippocampus and the amygdala from MRI 3D T1 brain scans. It has been validated in various populations including healthy controls and patients with Alzheimer’s disease, epilepsy and depression. It has been successfully applied to over 3,000 subjects, both controls, from adolescents to elderly subjects, and patients with different types of pathologies. The current stable version is fully automatic and focused on cross-sectional segmentation. The software can be used both as a command-line program or through a graphical user interface (GUI). The core of the program is coded in C++. It has a dependency to the AIMS library (http://www.brainvisa.info ) and preprocessing steps rely on processes in Matlab from SPM (http://www.fil.ion.ucl.ac.uk/spm/ ). The GUI is coded in Python and is based on BrainVISA (http://www.brainvisa.info ). The software has been registered at the APP (French agency for software protection).