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Section: New Results

Cardiac electrophysiology

Cardiac arrhythmia is a very frequent pathology that comes from an abnormal electrical activity in the myocardium. This pathology can be treated by catheterization and ablation of the malfunctionning cardiac tissue. The skills required for such interventions are still very challenging to learn, and typically acquired over several years. We first developed a training simulator for interventional electrocardiology and thermo-ablation of these arrhythmias. Based on physical models 9 , this training system reproduces the different steps of the procedure, including endovascular navigation, electrophysiological mapping, pacing and cardiac ablation. Based on a scenario of cardiac arrhythmia, cardiologists assessed the interactivity and the realism of our simulation. This work has been submitted in a journal and is currently under review.

Beyond electrophysiology training, our work around the cardiac electrophysiology also consisted in personalizing our mathematical models. Using the dense electrograms recorded intra-operatively, we presented an accurate and innovative approach to personalize our model, i.e. estimate patient-specific parameters. The modeling in silico of a patient electrophysiology is needed to better understand the mechanism of cardiac arrhythmia.