Section: New Software and Platforms

metamats_burden

Keywords: Metastasis - Cancer - Data assimilation - Regression - Biostatistics - Mechanistic modeling - Simulation

Scientific Description: This Matlab software is a minimal code for fitting simultaneously primary tumor growth and metastatic burden data using nonlinear mixed-effects modeling.

Functional Description: Set of functions for calibration of models of metastatic burden and primary tumor growth to empirical population data

News Of The Year: Submission to the French agency of software protection (APP). Inclusion of a new model for pre-operative anti-angiogenic treatment. Validation of the previous models on large databases (400+ animals)

• Participants: Sébastien Benzekry and Chiara Nicolo

• Partner: Roswell Park Comprehensive Cancer Center

• Contact: Sébastien Benzekry

• Publications: Modeling Spontaneous Metastasis following Surgery: An In Vivo-In Silico Approach - Computational Modelling of Metastasis Development in Renal Cell Carcinoma

• URL: http://metamats.bordeaux.inria.fr/