Section: Partnerships and Cooperations

European Initiatives

FP7 Projects


Participants : Benoît Bleuzé [correspondant] , Olivier Clatz, Maxime Sermesant, Nicholas Ayache.

medinria registration toolbox VPH NOE standards

  • Title: VPH NoE


  • Defi: Virtual Physiological Man

  • Instrument: Network of Excellence (NoE)

  • Duration: June 2008 - November 2012

  • Coordinator: University College London, UK

  • Others partners: Core members include UCL (UK), Oxford (UK), CNRS (FR), ULB (BE), U. of Nottingham (UK), UPF (ES), U. Auckland (NZ), EMBL (DE), U. Sheffield (UK), Karolinka (SE), ERCIM (FR), IOR (IT).

  • See also: http://www.vph-noe.eu/

  • Abstract: The Virtual Physiological Human Network of Excellence (VPH NoE) is a EU seventh Framework funded project, working to connect and support researchers in the VPH field within Europe and beyond. Inria is one of the core members, and is more dedicated, through Asclepios, to the data fusion part of the VPH toolkit. More precisely, a registration toolbox has been delivered which aims at including registration algorithms from the team and elsewhere into the new version of MedInria (2.x).

  • Title: euHeart


  • Defi: Virtual Physiological Man

  • Instrument: Integrated Project (IP)

  • Duration: June 2008 - May 2012

  • Coordinator: Philips Technologie GmbH Forschungslaboratorien (Germany)

  • Others partners: Philips Technologie GmbH (DE), The University of Oxford (UK), Universitat Pompeu Fabra (SP), The University of Sheffield (UK), Inria, French National Research Institute in Informatics and Mathematics (FR), King’s College London (UK), Academisch Medisch Centrum bij de Universiteit van Amsterdam (NL), Universität Karlsruhe (TH) (DE), Institut National de la Santé et de la Recherche Médicale, INSERM (FR), Philips Medical Systems Nederland BV (NL), Berlin Heart GmbH (DE), HemoLab BV (NL), Universitätsklinikum Heidelberg (DE), Volcano Europe SA / NV (BE), Hospital Clínico San Carlos de Madrid (SP), Philips Ibérica S.A. (SP)

  • See also: http://www.euheart.eu/

  • Abstract: The euHeart project (Ref 224495), is a 4-year integrated European project which aims at developing personalized, and clinically validated multi-physics, multi-level models of the heart and great vessels. Those models need to be tightly integrated with signal and image processing tools in order to assist clinical decision making and to help reducing morbidity and mortality rates associated with cardiovascular diseases. Asclepios is leading a workpackage on radiofrequency ablation for which electromechanical models of the heart are used to improve the planning of radiofrequency ablation lines for patient suffering from atrial fibrillation and ventricular tachycardia. The research performed in this project is partially described in section  6.4.3 and 6.4.4 .

  • Title: Biophysical Modeling & Analysis of Dynamic Medical Images

  • Type: IDEAS ()

  • Instrument: ERC Advanced Grant (Advanced)

  • Duration: April 2012 - March 2017

  • Coordinator: Inria (France)

  • See also: http://www.inria.fr/en/centre/sophia/news/medical-imagery-and-i.t.-the-personalised-digital-patient

  • Abstract: During the past decades, exceptional progress was made with in vivo medical imaging technologies to capture the anatomical, structural and physiological properties of tissues and organs in a patient, with an ever increasing spatial and temporal resolution. The physician is now faced with a formidable overflow of information, especially when a time dimension is added to the already hard to integrate 3-D spatial, multimodal and multiscale dimensions of modern medical images. This increasingly hampers the early detection and understanding of subtle image changes which can have a vital impact on the patient's health. To change this situation, this proposal introduces a new generation of computational models for the simulation and analysis of dynamic medical images. Thanks to their generative nature, they will allow the construction of databases of synthetic, realistic medical image sequences simulating various evolving diseases, producing an invaluable new resource for training and benchmarking. Leveraging on their principled biophysical and statistical foundations, these new models will bring a remarkable added clinical value after they are personalized with innovative methods to fit the medical images of any specific patient. By explicitly revealing the underlying evolving biophysical processes observable in the images, this approach will yield new groundbreaking image processing tools to correctly interpret the patient's condition (computer aided diagnosis), to accurately predict the future evolution (computer aided prognosis), and to precisely simulate and monitor an optimal and personalized therapeutic strategy (computer aided therapy). First applications will concern high impact diseases including brain tumors, Alzheimer's disease, heart failure and cardiac arrhythmia and will open new horizons in computational medical imaging.

Collaborations in European Programs, except FP7


Participants : Xavier Pennec [Correspondant] , Nicholas Ayache, Hervé Delingette, Kristin McLeod, Erin Stretton, Maxime Sermesant, Marco Lorenzi.

  • Program: ITEA2

  • Project acronym: Care4Me

  • Project title: Cooperative Advanced REsearch for Medical Efficiency

  • Duration: Sept. 2009 - Sept. 2013

  • Coordinator: Philips, NL.

  • Other partners: Alma (ES), Bull (FR), CEA (FR), CIMNE (ES), Compasiss (ES), CVSS (ES), Duodecim (FI), Erasmus MC (NL), ESI (NL), HSP (ES), Helsinki Hosp. (FI), ISI (GGR), LUMC (NL), MediConsult (FI), MEDIS (NL), Nokia (FI), Philips (NL), Pie Medical Imag. (NL), Pohjola (FI), Prowellness (FI), Robotiker (ES), UMC (NL), VTT (FI)

  • Abstract: This project aims at increasing quality and productivity in the healthcare care cycle by using more advanced medical imaging and decision support methods while combining them with different knowledge sources, from early diagnosis to treatment and monitoring. The final outcome of this project are clinical prototypes of novel medical image analysis and decision support systems for three specific disease areas (cancer, cardio-vascular and neurodegenerative diseases), that connect to the hospital information systems using a new system architecture. In this project, the role of the Asclepios team is to develop atlas of the ageing brain and the beating heart, and to model tumor growth.