Section: Partnerships and Cooperations

National Initiatives

IHU LIRYC

Our work is partially funded by the LIRYC project (ANR 10-IAHU 04).

• For 2013: the salary of M. Potse, member of Carmen, is payed by the LIRYC.

• The LIRYC gives us a partial financial support. In 2013: support to go to the conference IEEE EMBC in Osaka, Japan (http://embc2013.embs.org ), and partial support for a PhD jury.

• For 2012-2015: 1/2 PhD thesis associated to the project Modélisation pour les données multimodales (see section Regional Initiaves).

ANR HR-CEM

In 2013, we obtained a financial support for the project “High Resolution Cardiac Electrophysiology Models: HR-CEM” within the call for project « Modèles Numériques » of the ANR.

The scientific start of the project was on November, 4th, 2013.

It is an international project that involves three partners, Inria (coordinator), IHU LIRYC, and UMI-CRM at Montréal (Canada). The project has some external collaborators in Univ. Nantes, Univ. Pau and BCAM (Basque Center for Applied Math) at Bilbao (Spain).

Based on these collaborations and new developments in structural and functional imaging of the heart available at LIRYC, we plan to reconsider the concepts behind the models in order to improve the accuracy and efficiency of simulations. Cardiac simulation software and high-resolution numerical models will be derived from experimental data from animal models. Validation will be performed by comparing of simulation output with experimentally recorded functional data. The validated numerical models will be made available to the community of researchers that take advantage of in-silico cardiac simulation and, hopefully, become references. In particular we shall provide the first exhaustive model of an animal heart including the four chambers coupled through the special conduction network, with highly detailed microstructure of both the atria and the ventricles. Such a model embedded in high-performance computational software will provide stronger medical foundations for in-silico experimentation, and elucidate mechanisms of cardiac arrhythmias.

AMIES – Medic Activ

We were granted by the Agency AMIES a financial support to complete the one obtained from the Région Aquitaine for the Medic Activ project (see above). The objective of this support is to developp reduced order models of cardiac electrophysiology that might enter the MedicActiv framework. The difficulty is to define qualitatively realistic but fast numerical simulations of the ECG and cardiac function, for educational purpose.

ANR Labcom CardioXcomp

We are participant in the ANR Labcom project between Inria and the society Notocord (www.notocord.com ). At Inria, the proejct is leaded by JF. Gerbeau from the Reo team and we participate to the study and developpment of cardiac electrophysiology models suited to the context of the proejct.

The project is in its starting phase in 2013: the objective of the first 6 months is to define precisely the nature and objectives of the common laboratory between Inria and Notocord. A contract is planned to be signed after these 6 months, and the ANR financial support to be granted at that time.