Section: New Results

Ancestral gene order reconstruction

• In the field of genomic rearrangement, a topic of interest is to infer ancestral gene order from gene order known in extant species. The problem resumes to compute a set ancestral CARs (continuous ancestral regions) at a given node of a phylogeny. We designed a progressive homology-based method which iteratively detects and assembles ancestral adjacencies while allowing some micro-rearrangements of synteny blocks at the extremities of the progressively assembled CARs. Comparing with other methods we are able to produce more robust CARs with a very simple and efficient method. This work was published in [7] .