Section: New Software and Platforms

QuantEv

Keyword: Biomedical imaging

Functional Description:  The QuantEv software is dedicated to the analysis of the spatial distribution of intracellular events represented by any static or dynamical descriptor (e.g. detected points, segmented regions, trajectories...), provided that the descriptors are associated with spatial coordinates. QuantEv first computes 3D histograms of descriptors in a cylindrical coordinate system with computational cell shape normalization, enabling comparisons between cells of different shape. Densities are obtained via adaptive kernel density estimation, and we use the Circular Earth Mover's Distance to measure the dissimilarity between densities associated to different experimental conditions. A statistical analysis on these distances reliably takes into account the biological variability over replicated experiments.

• Participants: Thierry Pécot, Charles Kervrann, Jean Salamero.

• Contact: Thierry Pécot, Charles Kervrann.

• On-line demo:  http://mobyle-serpico.rennes.inria.fr/cgi-bin/portal.py#forms::...

• Languages:  C/C++ and Java (plug-in Icy : http://icy.bioimageanalysis.org).