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Bilateral Contracts and Grants with Industry
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Section: New Software and Platforms

TubuleJ

Keywords: Bioinformatics - Biomedical imaging

Functional Description:  The TubuleJ software written in java (plug-in ImageJ) is devoted to the analysis of microtubules and helical structures in 2D cryo electron microscope images. The software straightens curved microtubule images by estimating automatically point locations on the microtubule axis. The estimation of microtubule principal axis relies on microtubule cylindrical shape analyzed in the Fourier domain. A user-friendly interface enables to filter straight fiber images by selecting manually the layer lines of interest in the Fourier domain. This software can be used to generate a set of 2D projection views from a single microtubule projection view and a few parameters of this microtubule structure.