Section: Partnerships and Cooperations

International Initiatives

Informal International Partners

Collaboration with Max-Planck Institute, Martinsried (Germany), Dr. Julio Ortiz and Antonio Martinez: Detection and segmentation of macromolecules in cryo-electron tomography (project in progress with Emmanuel Moebel and Charles Kervrann).

Collaboration with Aalborg University (Denmark), Prof. Rasmus Waagepetersen: Estimating equations for inhomogeneous determinantal point processes (project with Frédéric Lavancier).

Inria Associate Teams Not Involved in an Inria International Labs

CytoDI Inria Associated-Team

• Title: Quantitative Imaging of Cytoskeleton Dynamics in 3D

• International Partner:

  • University of Texas, SouthWestern Medical Center, Dallas (United States) - Gaudenz Danuser

• Start year: 2016

• See also: http://serpico.rennes.inria.fr/doku.php?id=research:cytodi

• Participants: Sandeep Manandhar, Patrick Bouthemy, Charles Kervrann.

• The main scientific goal of the Associated-Team is the spatiotemporal characterization and comparison of cytoskeleton networks involved in cell migration and observed through live cell imaging in three dimensions (3D). Those networks include the cytoskeleton, i.e., microtubules (MT), intermediate filaments (IF), dynamically resolvable by Bessel Beam Light Sheet fluorescent microscopy. The goal will be achieved through the design of local and global descriptors of the spatial conformation and deformation of the cytoskeleton. Subsequently, general metrics to compare and classify the MT and IF networks will be investigated. This study will be carried out on oncogenically transformed lung cancer epithelial cells.

  The second meeting of the AT CytoDI took place in Rennes in July 2017 (visit of P. Roudot and K. Dean), to discuss and update current research direction and discuss scientific progress. Several meetings were organized with students (S. Manandhar, V. Briane, E. Moebel, T. Dubois, Q. Delannoy) to synchronize development in optical flow, co-orientation and visualization. The Danuser team focused on presenting recent imaging and analysis capacities as well as the current solution in development for the systematic analysis, contextualization and interpretation of 3D dynamics for quantitative biology.