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Section: New Software and Platforms
autoMRI
Keywords: FMRI - MRI - ASL - FASL - SPM - Automation
Scientific Description: This software is highly configurable in order to fit a wide range of needs. Pre-processing includes segmentation of anatomical data, as well as co-registration, spatial normalization and atlas building of all data types. The analysis pipelines perform either within-group analysis or between-group or one subject-versus-group comparison, and produce statistical maps of regions with significant differences. These pipelines can be applied to structural data to exhibit patterns of atrophy or lesions, to ASL (both pulsed or pseudo-continuous sequences) or PET data to detect perfusion or metabolic abnormalities, to relaxometry data to detect deviations from a template, to functional data - either BOLD or ASL - to outline brain activations related to block or event-related paradigms. In addition to the standard General Linear Model approach, the ASL pipelines implement an a contrario approach and, for patient-specific perfusion study, an heteroscedastic variance model. Besides, the vascular pipeline processes 4D MRA data and enables accurate assessment of hemodynamic patterns.
Functional Description: AutoMRI Based on MATLAB and the SPM8 toolbox, autoMRI provides complete pipelines to pre-process and analyze various types of images (anatomical, functional, perfusion, metabolic, relaxometry, vascular).