Section: Software

Pathtastic: Inference of whole-genome metabolic models

Participants : David James Sherman [correspondant] , Pascal Durrens, Nicolás Loira, Anna Zhukova.

Pathtastic is a software tool for inferring whole-genome metabolic models for eukaryote cell factories. It is based on metabolic scaffolds, abstract descriptions of reactions and pathways on which inferred reactions are hung are are eventually connected by an interative mapping and specialization process. Scaffold fragments can be repeatedly used to build specialized subnetworks of the complete model.

Pathtastic uses a consensus procedure to infer reactions from complementary genome comparisons, and an algebra for assisted manual editing of pathways.

For more information see pathtastic.gforge.inria.fr , the Pathtastic Gforge web site.