Section: New Results

RNA-Seq software benchmarking

Plenty of methods have been devised to analyze RNA-Seq data. Due to this large choice, it is a difficult task to determine what software is the best suited for a given question. To help in solving this problem, with colleagues at IRMB and in the SeqOne start-up in Montpellier, we devised a flexible benchmarking pipeline [18].

This pipeline is intended to be flexible enough to deal either with simulated or real data and to evaluate software on many possible aspects (mapping, splice detection, fusion detection, variant calling, and also on the post-analysis aspects such as gene quantification).