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  • The Inria's Research Teams produce an annual Activity Report presenting their activities and their results of the year. These reports include the team members, the scientific program, the software developed by the team and the new results of the year. The report also describes the grants, contracts and the activities of dissemination and teaching. Finally, the report gives the list of publications of the year.

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Section: New Results

Optimizing CRN robustness

Participants : François Fages, Lucia Nasti, Sylvain Soliman.

In [7] we present two complementary notions of robustness of a system with respect to a property of its behaviour expressed in temporal logic: first the statistical notion of model robustness to parameter perturbations, defined as its mean functionality; and second, a metric notion of formula satisfaction robustness, defined as the penetration depth in the validity domain of the temporal logic constraints. We show how the formula robustness can be used in BIOCHAM-4 with no extra cost as an objective function in the parameter optimization procedure, to actually improve CRN robustness. We illustrate these unique features with a classical example of the hybrid systems community and provide some performance figures on a model of MAPK signalling with 37 parameters.