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Section: Software

Regliss – RNA locally optimal structures

Actively developped in 2011.

Software self-assessment: A-2, SO-4, SM-2, EM-2, SDL-4, DA-4, CD-4, MS-4, TPM-4

Software web site : http://bioinfo.lifl.fr/RNA/regliss/

Regliss is a tool that studies the energy landscape of a given RNA sequence by considering locally optimal structures. Locally optimal structures are thermodynamically stable structures that are maximal for inclusion: they cannot be extended without producing a conflict between base pairs in the secondary structure, or increasing the free energy. The tool generates all locally optimal structures in a given sequence. Moreover, Regliss can be used to explore the neighborhood of structures through an energy landscape graph.