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  • The Inria's Research Teams produce an annual Activity Report presenting their activities and their results of the year. These reports include the team members, the scientific program, the software developed by the team and the new results of the year. The report also describes the grants, contracts and the activities of dissemination and teaching. Finally, the report gives the list of publications of the year.

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Section: New Results

Generalizing a mathematical model of prion aggregation allows strain coexistence and co-stability by including a novel misfolded species

Prions are proteins capable of adopting misfolded conformations and transmitting these conformations to other normally folded proteins. A distinct feature of prion propagation is the existence of different phenotypical variants, called strains. In order to conform to biological observations of strain coexistence and co-stability, we develop in [19] an extension of the classical model by introducing a novel prion species consistent with biological studies.